Past Issues

2023: Volume 2, Issue 1

Myelinated Retinal Nerve Fibers, a Complicating Factor in Amblyopia Rehabilitation?

Tristan Jurkiewicz1,2,*

1Centre d’Exploration de la Rétine Kléber (CERK), 50 cours Franklin Roosevelt, 69006 Lyon, France

2Centre de Recherche en Neurosciences de Lyon (CRNL), Université de Lyon, 69500 Bron, France

*Corresponding author: Tristan Jurkiewicz, Centre d’Exploration de la Rétine Kléber (CERK), 50 Avenue Franklin Roosevelt 69006 Lyon, France; Tel: +33684893943; Email: [email protected]

Received Date: April 28, 2023

Publication Date: May 18, 2023

Citation: Jurkiewicz T. (2023). Myelinated Retinal Nerve Fibers, a Complicating Factor in Amblyopia Rehabilitation? Cases. 2(1):11.

Copyright: Jurkiewicz T. © (2023).


Myelinated retinal nerve fibers (MRNFs) have the appearance of white striated patches with poorly defined borders and are considered like a benign congenital anomaly. In this clinical case, a 25-year-old patient presented for an optical correction renewal. During the examination an amblyopia in the right eye was found associated with extensive MRNFs in the superotemporal region of the retina. In his childhood an amblyopia rehabilitation therapy was performed with partial recovery. The persistence of amblyopia despite appropriate treatment could be due to the presence of extended MRNFs.

In the literature the most common association of MRNFs are with amblyopia, ametropia and/or strabismus. In those cases the rehabilitation seems to be less effective, a treatment more aggressive is recommended with refraction under cycloplegia and total occlusion adapted to the patient's age. The presence of extended MRNFs would not be the cause of amblyopia but it seems to be a complicating factor in the visual prognosis. The main prognostic elements, as in the case of isolated amblyopia, are the initial visual acuity and the magnitude of anisometropia.

Keywords: Myelinated Retinal Nerve Fibers, Amblyopia, Occlusion Therapy

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